The present invention describes a novel herbomineral formulation useful for effective management of iron overload initiated complications including steatohepatitis. The novel herbomineral formulation has been shown to be organ oprotective as shown by normalization of various organ weights including that of liver and spleen. The herbomineral formulation has also been shown to cause remarkable recovery on iron overload induced changes in biochemical parameters. In Thalassemia major patients, with a history of blood transfusions, the herbomineral formulation has shown significant improvements in quality of life, specifically in chronic fatigue. In a further aspect, the present invention relates to preparation of herbomineral formulation with other active agents.
