APPLICATION OF 20(S)-PROTOPANAXADIOL IN PREPARATION OF ANTIDEPRESSANTS

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专利权人:

Yongzheng Hui

发明人:

Yongzheng Hui,Zirong Yang,Zhiqi Yang,Qiang Ge

申请号：

US13404014

公开号：

US20120214779A1

申请日:

2012.02.24

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention provides the novel use of 20(S)-protopanaxadiol in the preparation of medicaments for the treatment of depressive psychiatric disorders. The pharmacological test results indicated that the compound could remarkably increase the level of NE, 5-HT and HAV in the brains of model rats having depressive disorders, remarkably enhance tremors induced by 5-hydroxytryptophan (5-HTP) and behavioral effects induced by levodopa, and inhibit the re-uptake of 5-HT and NA.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/