Degenhardt, Matthias,Rosenberg, Jorg,Breitenbach, Jorg,Schmidt, Christoph,Krull, Harald,Kessler, Thomas
申请号：
AU2007224486
公开号：
AU2007224486B2
申请日:
2007.03.12
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A process for producing a solid dispersion of an active ingredient which comprisesfeeding the active ingredient and a matrix-forming agent to an extruder and forminga uniform extrudate, wherein the extruder comprises at least two rotating shafts(2), each of the shafts (2) carrying a plurality of processing elements disposedaxially one behind the other, the processing elements defining (i) a feedingand conveying section (A), (ii) at least one mixing section (B), and (iii) a dischargingsection (E), wherein the processing element(s) defining the mixing section(B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw typeelement (figure 2).
