Identification of LKB1 mutation as a Predictive Biomarker for sensitivity to Tor Kinase Inhibitors

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专利权人:

SIGNAL PHARMACEUTICALS; LLC

发明人:

SANKAR, SABITA,CHOPRA, RAJESH,XU, WEIMING,NING, YUHONG,XU, SHUICHAN

申请号：

CR20120406

公开号：

CR20120406A

申请日:

2012.08.03

申请国别(地区):

CR

年份:

2012

代理人:

摘要：

The present methods are provided to treat and / or prevent a cancer or a tumor Syndrome in a patient, comprising administering an effective amount of an inhibitor of Tor kinase to a patient that he has cancer or a tumor Syndrome, characterized by a loss or mutation of the gene Or LKB1 Protein and / or AMPK.Se proporcionan en la presente métodos para tratar y/o prevenir un cáncer o un síndrome tumoral en un paciente, que comprende administrar una cantidad efectiva de un inhibidor de TOR cinasa a un paciente que tiene cáncer o un síndrome tumoral, caracterizado por una pérdida o mutación del gen o proteína LKB1 y/o AMPK.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/