Lyophilized pharmaceutical composition with improved reconstitution time containing taxane derivative and process for its preparation

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专利权人:

エスケー ケミカルズ カンパニー リミテッド

发明人:

ジャン ウー ジェ,オー ジュン ギョ,フワン ヨン ユン,チョイ ウォン ジェ,ウム キー アン

申请号：

JP2010534893

公开号：

JP5535929B2

申请日:

2008.11.21

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention relates to a lyophilized composition with an improved reconstitution time comprising a taxoid and a method thereof. More specifically, the present invention relates to a lyophilized composition with an improved reconstitution time prepared by mixing and dissolving a taxoid； cyclodextrin (CD)； a hydrophilic polymer selected from the group consisting of hydroxypropylmethyl CeIIuIoSe (HPMC), polyethylene glycol (PEG), and polyvinylpyrrolidone (PVP)； and a bulking agent of saccharides in water for injection； and lyophilizing the mixture, and a method thereof.

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中国工程科技知识中心

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http://www.ckcest.cn/home/