< Topic >The usefulness, the new chemical compound which possesses nerve cell projection extension action is offered to prevention or remedy of the nervous denaturation type disease.SolutionsNext formula (i)< Conversion 1 >[In formula, X displays OR or NR1 R2, Y, OH and NR3 R4, nhc (=NH) NHR5 or displays nhc (=NH) R5, Z, the hydrogen atom, direct condition or the carbon atom which diverges several the alkyl group or the nitrogen atom, the sulfur atom or the oxygen atom of 1 or 5 displays the aryl basis of 5 or 6 member rings which 1 or 2 characteristics it can do. ] With the chemical compound which is displayed or that medicine or the salt which is allowed veterinary medicine.< Selective figure >It is not【課題】神経変性系疾患の予防又は治療に有用な、神経細胞突起伸展作用を有する新規化合物を提供する。【解決手段】次式(I)【化1】[式中、Xは、OR又はNR1R2を表し、Yは、OH、NR3R4、-NHC(=NH)NHR5又は-NHC(=NH)R5を表し、Zは、水素原子、直鎖状の若しくは分岐した炭素原子数1ないし5のアルキル基又は窒素原子、硫黄原子若しくは酸素原子を1若しくは2個有し得る5若しくは6員環のアリール基を表す。]で表される化合物又はその医薬的又は獣医学的に許容される塩。【選択図】なし