Wei HE;Victoria LOMBARDO;Joseph BARBOSA;Praveen PABBA;Kenneth Gordon CARSON;James TARVER, JR.;Michael Walter GARDYAN
发明人:
Joseph BARBOSA,Kenneth Gordon CARSON,Michael Walter GARDYAN,Wei HE,Victoria LOMBARDO,Praveen PABBA,James TARVER, JR.
申请号：
US13231653
公开号：
US20120065200A1
申请日:
2011.09.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds are disclosed for the treatment, management and prevention of diseases and disorders affecting the bone. Particular compounds are potent inhibitors of Notum Pectinacetylesterase, and are of the formula:wherein E, G, Y, Z, R1, R2, and R3 are defined herein.
