Giuseppe Mazza,Walld Al-Akkad,Massimo Pinzani,Toby Proctor
申请号:
US15748390
公开号:
US20180214609A1
申请日:
2016.07.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This invention relates to a method of producing a decellularised tissue scaffold which comprising treating a sample of tissue with an osmotic reagent and a detergent whilst subjecting the tissue sample to oscillation with a displacement of 1 mm or more and a frequency of 3 Hz or more during these treatment steps. This method may be useful in producing acellular scaffolds that maintain the 3-D architecture and extracellular matrix composition and morphology of the native tissue.