USE OF PRG4 AS AN ANTI-INFLAMMATORY AGENT

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专利权人:

LUBRIS LLC

发明人:

JAY, Gregory, D.,SULLIVAN, Benjamin, D.,SCHMIDT, Tannin, Avery,ELSAID, Khaled,TRUITT, Edward, R.,KRAWETZ, Roman,SZMYDYNGER-CHODOBSKA, Joanna,CHODOBSKA, Adam,FAREED, Jawed

申请号：

SG11201705636S

公开号：

SG11201705636SA

申请日:

2016.01.26

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

Disclosed herein are methods of using PRG4 glycoprotein, also known as lubricin, to reduce, inhibit, or down-regulate pro-inflammatory pathways in patients at risk of or suffering from an inflammatory response or allergy symptom through CD44 antagonization, regulating pro-inflammatory cytokine production, inhibiting NF-κB translocation and/or facilitating removal of inflammation-inducing cellular or matrix debris or allergens.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/