INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/162923 Al 28 September 2017 (28.09.2017) WIPO I PCT 111111111111110111011111111111010111110111011111111011111010111011111111111110111111 W O 20 17 / 16 29 23 Al (51) International Patent Classification: C12P 19/00 (2006.01) C12P 19/12 (2006.01) C12P 19/02 (2006.01) (21) International Application Number: PCT/FI2017/050201 (22) International Filing Date: 22 March 2017 (22.03.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 20165250 24 March 2016 (24.03.2016) FI (71) Applicant: UPM-KYMMENE CORPORATION [MI]; Alvar Aallon katu 1, 00100 Helsinki (FI). (72) Inventors: TURUNEN, Sami; Variksenmarjankatu 5, 53500 Lappeenranta (FI). TAMPER, Juha; Savilandentie 1187, 54930 Levanen (FI). (74) Agent: PAPULA OY; P.O. Box 981, 00101 Helsinki (FI). (81) Designat