PROBLEM TO BE SOLVED: To achieve a heterogeneous system liquid phase catalyst oxidation reaction of high selectivity and high yield which can inhibit excessive oxidation to stop the reaction in a predetermined partial oxidation stage.SOLUTION: This invention provides a heterogeneous system liquid phase oxidation reaction method using an oxidizing agent in the presence of an oxidation reaction catalyst of an organic reaction substrate, wherein an adsorbent capable of adsorption collection of an organic reaction product in the predetermined partial oxidation stage coexists.