David Alsop,Elena Vinogradov,Aaron K. Grant,Robert E. Lenkinski
申请号：
US14089183
公开号：
US20140079641A1
申请日:
2013.11.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T1 greater than 15 seconds and a water-octanol partition coefficient between −1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, the imaging agent includes a carbon-13 enriched alcohol.
