Auristatins having an aminobenzoic acid unit at the N terminus
- 专利权人:
- Svetlana O. Doronina
- 发明人:
- Svetlana O. Doronina,Brian A. Mendelsohn
- 申请号:
- US11667437
- 公开号:
- US08288352B2
- 申请日:
- 2005.11.14
- 申请国别(地区):
- US
- 年份:
- 2012
- 代理人:
- 摘要:
- Auristatin-type peptides are disclosed which are highly cytotoxic, synthetically accessible, and can be conjugated to antibodies and other ligands.
- 来源网站:
- 中国工程科技知识中心