Troy W. McCall;Steve Labudzinski;Lirong Liu;Anand R. Baichwal
发明人:
Anand R. Baichwal,Troy W. McCall,Lirong Liu,Steve Labudzinski
申请号：
US11729024
公开号：
US08679535B2
申请日:
2007.03.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed are sustained release oral solid dosage forms comprising a therapeutically effective amount of a medicament having a solubility of more than about 10 g/l； a pH modifying agent； and a sustained release matrix comprising a gelling agent, said gelling agent comprising a heteropolysaccharide gum and a homopolysaccharide gum capable of cross-linking said heteropolysaccharide gum when exposed to an environmental fluid, said dosage form providing a sustained release of said medicament after oral administration to human patients.
