An image compensation system and method which provided to compensate echo signals acquired from an ultrasound probe which are provided in the present invention. M channels of the ultrasound probe are divided into m groups where each group consists of n channels. For each group, image compensation system takes the average value from n channel data to achieve an average-signal strength echo signal and then computes n error values according to the average-signal strength echo signal and n echo signals within a group. The image compensation system determines n plus and minus sign operators according to the positivity or negativity of the n error values. The image compensation system then calculates a mean absolute error value according to the n error values. Thereafter, n compensated echo signals of the m groups according to the average-signal echo strength, plus and minus sign operators, and the mean absolute error value are digitized.