Pieczykolan Jerzy Szczepan,Lemke Krzysztof Kazimierz,Pawlak Sebastian,Źerek Bartłomiej
申请号：
NZ60921611
公开号：
NZ609216A
申请日:
2011.12.05
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a fusion protein comprising: domain (a) which is a functional fragment of hTRAIL protein sequence, said fragment beginning with an amino acid at a position not lower than hTRAIL95, or a sequence having at least 70% sequence identity with said functional fragment； and domain (b) which is a sequence of an immunostimulating effector peptide selected from the group consisting of the pseudodimer of interferon gamma of SEQ. No. 19 and the pseudodimer of interferon alpha 2b of SEQ. No. 46； wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a), and the sequence identities are as disclosed in the specification.
