Disclosed herein are piperazine-substituted benzothiophene quinoline compounds of formula I where the substituents are as defined herein for example 7-[4-(4-benzo[b]thiophen-4-ylpiperazin-1-yl)butoxy]-1-hydroxymethyl-3,4-dihydro-1H-quinolin-2-one. The compounds are intended to have improved solubility in oil such as sesame oil and benzyl benzoate, which has a broader treatment spectrum, causes less side effects, and is superior in tolerability and safety, and use thereof.
