This Hair bright Real, which is applied, provides the Duo Seed Drug Learn Drug Elixirs Group methods for closing the methods and Zhi Treatment Worry Yu disease Huo Smoke Addiction of oral Drug Elixirs Group conjunctions object such as Wu, System Prepare Zhu such as Yan Long Buddhism Fang Xing Group conjunctions objects on Li great Body. Ti Gong mono- Seed are formulated comprising a He Xin With mono- Tu Layer Drug Learn in the bright state Sample of this Hair, and containing bupropion, (bupropion , Huo Said Bupropions) are Ji Qi Which Class derivatives in The cores. The Tu Layer may include that the acceptable pH value of 5% to 99% weight percent Drug Learn of The Tu Layer weight Zhong Approximately Accounting is non-according to Lai polymer. The Tu Layer can further include the interfacial activity Elixirs of 0.001% to 30% weight percent of The Tu Layer weight Zhong Approximately Accounting. The method that the oral Elixirs types Drug Learn Group of the bright another Tai Sample Department Ti Gong System Prepare With applications Yi Seed Zhu such as Ingot Elixirs etc. of this Hair close object.本發明之實施例大體上提供多種藥學藥劑組合物、製備諸如延長釋放型組合物等口服藥劑組合物的方法以及治療憂鬱症或煙癮的方法。本發明一態樣中提供一種包含一核心與一塗層的藥學配方,該核心中含有丁胺苯丙酮(bupropion,或稱安非他酮)及其鹽類衍生物。該塗層可包含在該塗層重量中約佔5%至99%重量百分比的藥學可接受之pH值非依賴性聚合物。該塗層可更包含在該塗層重量中約佔0.001%至30%重量百分比之界面活性劑。本發明另一態樣係提供製備與施用一種諸如錠劑等口服劑型之藥學組合物的方法。
