Ras inhibitors

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专利权人:

发明人:

申请号：

EP12170715.2

公开号：

EP2671575A1

申请日:

2012.06.04

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to compounds which inhibit the protein product Ras of the proto-oncogene ras, more particularly Ras-effector interaction, by stabilizing conformational state 1(T) of Ras GTP having a decreased effector affinity. It further relates to the use of these compounds as medicaments and anti-tumor agents and to pharmaceutical compositions comprising such compounds.

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