Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof

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专利权人:

发明人:

Daria Mochly-Rosen,Che-Hong Chen,Xiaohu Ouyang

申请号：

US14520098

公开号：

US09273025B2

申请日:

2014.10.21

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides compounds that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. The present invention further provides assays for identifying agonists of ALDH2.

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