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ПОВЫШЕНИЕ БИОДОСТУПНОСТИ ЛЕКАРСТВЕННЫХ СРЕДСТВ ПРИ ТЕРАПИИ НАЛТРЕКСОНОМ
专利权人:
ОРЕКСИДЖЕН ТЕРАПЬЮТИКС; ИНК. (US)
发明人:
ФЛАНАГАН Шон (US),ДУНАЕВИЧ Эдуардо (US)
申请号:
RU2013127423/15
公开号:
RU2013127423A
申请日:
2011.12.02
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of treating overweight or obesity, comprising: identifying a subject suffering from overweight or obesity and introducing said subject a therapeutically effective amount of a food naltrexone or a pharmaceutically acceptable salt thereof and bupropion or a pharmaceutically acceptable soli.2. A method for increasing the bioavailability of drugs in combination therapy with naltrexone / bupropion aimed at weight loss, comprising: providing a subject with a therapeutically effective amount of naltrexone or a pharmaceutically acceptable salt thereof and bupropion or a pharmaceutically acceptable salt thereof providing said subject with food and introducing said subject said therapeutically effective amount of naltrexone or a pharmaceutically acceptable salt thereof and bupropion or a pharmaceutically acceptable salt with said food, the bioavailability of said naltrexone or pharmaceutically acceptable salt thereof is increased compared to the bioavailability of the same amount of said naltrexone or pharmaceutically acceptable salt thereof, introduced without food or bioavailability of said bupropion or a pharmaceutically acceptable salt increases Xia compared to bioavailability of the same quantity of said bupropion or a pharmaceutically acceptable salt, introduced without pischi.3. A method according to Claim. 1 or 2, characterized in that the amount of said naltrexone or pharmaceutically acceptable salt thereof is in the range from about 4 mg to about 32 mg per sutki.4. A method according to claim. 3, characterized in that said subject is overweight or ozhireniem.5.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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