Interleukin 8 (il-8) som prognostisk och prediktiv biomarkör samt kompositioner och vektorer för att användas vid onkolytisk immunterapi

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专利权人:

TILT Biotherapeutics Oy

发明人:

Taipale, Kristian,Hemminki, Akseli

申请号：

FI20165814

公开号：

FI20165814A

申请日:

2016.10.27

申请国别(地区):

FI

年份:

2018

代理人:

摘要：

The present invention relates to an oncolytic viral vector comprising a nucleic acid sequence encoding an anti-interleukin 8 neutralizing antibody.Further, the present invention relates to use of interleukin 8 as a prognostic and predictive biomarkerin oncolytic immunotherapy. In this respect, the present invention is directed to a method ofanalysing whether a subject suffering from a cancer is responsive or non-responsive to the treatment with an oncolytic viral vectorand to a method of monitoringefficacy of an oncolytic immunotherapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/