Abstract The present invention relates to a natural composition (weedicide) formulation to be used in farming or agriculture purpose, particularly for control and prevention of agriculture pests and insects. The natural compositions containing a novel combination of calcium oxide (Neetukakka), rock salt, cow urine, water and one or more plant essential oils (Neem oil) and/or derivatives thereof, natural or synthetic, as a fumigant pesticide. The natural composition (weedicide) is cost effective, safer, eco friendly and can be also used as bio fertilizer, fungicide, etc.