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Orally fast disintegrating tablets and a method of manufacturing the same
专利权人:
田辺三菱製薬株式会社
发明人:
杉本 昌陽,北岡 健一,齊藤 泰紀,上村 勝治
申请号:
JP2013129754
公开号:
JP5722953B2
申请日:
2013.06.20
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
Disclosed is an orally rapidly disintegrating tablet characterized in that the tablet can be produced in a conventional tablet manufacturing facility and has a satisfactory level of hardness for practical applications, and the change in properties of the tablet (i.e., decreased in hardness of the tablet, and delay of the disintegration time of the tablet in the oral cavity) are rarely caused by factors such as humidity. The orally rapidly disintegrating tablet has hardness of 40N or more, can be disintegrated in the oral cavity within 60 seconds, and is produced by compressing of a mixture of (a) an active ingredient, (b) an excipient having good water wettability, (c) a water-insoluble polymer that is well compactible and does not substantially cause a decrease in the water wettability of the excipient and (d) a disintegrating agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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