PETITES MOLÉCULES POUR LA MODULATION DE MCL-1 ET PROCÉDÉS DE MODULATION DE LA MORT CELLULAIRE, LA DIVISION CELLULAIRE, LA DIFFÉRENCIATION CELLULAIRE ET PROCÉDÉS DE TRAITEMENT DE TROUBLES

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专利权人:

INC.;DANA-FARBER CANCER INSTITUTE

发明人:

WALENSKY, LOREN, D.,STEWART, MICHELLE, L.,COHEN, NICOLE

申请号：

EP11737834

公开号：

EP2528893A4

申请日:

2011.01.31

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for modulating MCL-1 activity and for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders and/or for enhancing cellular engraftment and/or wound repair, as a sole agent or in combination with other active ingredients.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/