The present invention provides a compound of Formula (I):or a pharmaceutically acceptable salt thereof. Also, the present invention provides a pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof with a pharmaceutically acceptable diluent or carrier. The present invention further provides methods for treating abdominal aortic aneurysm, plaque instability, atherosclerosis, or autoimmune disorders such as rheumatoid arthritis, psoriasis, and lupus comprising administering a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.本發明提供式(I)化合物:或其醫藥學上可接受之鹽。又,本發明提供一種醫藥組合物,其包含式(I)化合物或其醫藥學上可接受之鹽與醫藥學上可接受之稀釋劑或載劑。本發明進一步提供治療腹主動脈瘤、斑塊不穩定、動脈粥樣硬化或自體免疫病症(諸如類風濕性關節炎、牛皮癬及狼瘡)之方法,其包含投與治療有效量之式(I)化合物或其醫藥學上可接受之鹽或包含式(I)化合物或其醫藥學上可接受之鹽及醫藥學上可接受之稀釋劑或載劑的醫藥組合物。