The present invention relates to granules comprising a solid core on which an active ingredient is supported, said core being chosen preferably from among insoluble supports, said granules also comprising, supported on said solid core, the following compounds: one or more colouring agents, one or more metallic pigments, one or more gas-releasing compounds, and optionally one or more embittering agents.本發明有關包含載有活性成分之固態核心的顆粒,該核心較佳係選自不溶解載體,該顆粒亦包含載於該固態核心上之下列化合物:一或多種著色劑、一或多種金屬顏料、一或多種釋放氣體之化合物,及選擇性地一或多種苦味劑。