Juan Wang,Chandir Ramani,Joe Lambing,Christine Ye,Elizabeth Vadas,Julian Taillemite,Marie-Pierre Filliot,Dieter Becker
申请号：
US13521906
公开号：
US20130165459A1
申请日:
2011.01.12
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is concerned with a solid delivery form of elinogrel for the treatment of thrombosis which is notable for its multi-pH dissolution, immediate release and improved pharmacokinetic properties and stability in storage. The delivery and dosage form is a solid, oral formulation comprising: a) at least about 15% by weight elinogrel or a pharmaceutically acceptable salt thereof relative to the total weight of the overall pharmaceutical composition, and b) at least one pharmaceutically acceptable carrier. A further aspect of the present invention concerns the preparation and use of such a formulation.
