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NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS
专利权人:
4SC AG
发明人:
MULLER, MATTHIAS,MULLER, BERND,MAIER, THOMAS
申请号:
NZ58782409
公开号:
NZ587824A
申请日:
2009.03.11
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein is a process for the preparation of N-sulphonylpyrrole derivatives of formula I, wherein the substituents are as defined within the specification, comprising the step of reacting an acrylic acid chloride compound of formula II with aqueous hydroxylamine. The process further includes the steps of transforming the compound of formula II into its acid chloride of formula II.
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