FAN PINGCHEN,GREENMAN KEVIN LLOYD,LELETI MANMOHAN REDDY,LI YANDONG,POWERS JAY,TANAKA HIROKO,YANG JU,ZENG YIBIN
申请号:
PL09835688
公开号:
PL2381778T3
申请日:
2009.12.21
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
A process for preparing a compound of formula (ii), comprising (a) treating a compound of formula (i) with H 2 and a platinum oxide catalyst under reducing conditions; and (b) subjecting the product of step (a) to resolution with di-toluoyl-L-tartaric acid to provide compound (ii) in about 97% enantiomeric excess.