BAYLOR COLLEGE OF MEDICINE;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
TWEARDY, DAVID J.,KASEMBELI, MOSES M.,XU, MARVIN X.,MILNER, JOSH,BOCCHINI, CLAIRE E.
申请号:
CA2918264
公开号:
CA2918264A1
申请日:
2014.07.18
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Embodiments of the invention include methods of preventing and/or reducing the risk or severity of an allergic reaction in an individual. In some embodiments, particular small molecules are employed for prevention and/or reduction in the risk or severity of anaphylaxis. In at least particular cases, the small molecules are inhibitors of STAT3. In some cases, the small molecule comprises N-(1',2-dihydroxy-1,2'-binaphthalen-4'-yl)-4-methoxybenzenesulfonamide.