Disclosed is a power supply device for electronic atomizer, which includes a housing having a battery compartment formed therein, at least a battery installed in the battery compartment and a control circuit having an input side electrically connected with the battery and an output side electrically connected with an output electrode terminal. The control circuit includes a microcontroller unit, a mode selection module connected with the microcontroller unit for selecting working mode of the electronic atomizer, a regulation module connected with the microcontroller unit for regulating working parameter of the electronic atomizer and a start button connected with the microcontroller unit for controlling whether the electronic atomizer starts up. The mode selection module is a multi-position switch and the microcontroller unit is able to being triggered to start corresponding working modes by switching the multi-position switch to be different positions. The present invention has the advantage of convenient to use.