METHOD FOR THE REALIZATION OF A BIOCOMPATIBLE BONE IMPLANT COMPRISING GRANULAR ELEMENTS AND A BIOREABSORBABLE BIOPOLYMER GEL AND BIOCOMPATIBLE BONE IMPLANT THUS OBTAINED
Francesco Bucciotti,Marzio Piccinini,Susanna Prosperi
申请号：
US14384977
公开号：
US20150050326A1
申请日:
2013.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Method for providing a biocompatible bone implant adapted to fill a bone cavity or lacuna including the steps of providing granular elements in form of granules and/or granule aggregates, providing at least one primary polymeric solution including a biopolymer, at least partly coating the granular elements with the primary polymeric solution, obtaining coated granular elements including a biopolymer coating, providing a cross-linking solution, dipping the coated granular elements in the cross-linking solution, waiting a period of time referred to as “jellification time” of between 30 seconds and 1 hour, in which during said waiting step there occurs the cross-linking of the biopolymer coating of the granular elements with the cross-linking solution and the jellification of the coating, with the aim of obtaining a cohesive biocompatible implant including granular elements and a bio-reabsorbable biopolymer gel biocompatible bone implant obtained through such method.
