The Board of Trustees of the Leland Stanford Junior University
发明人:
Mark A. Kay,Nicole K. Paulk
申请号：
US15681267
公开号：
US20170360962A1
申请日:
2017.08.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to variant AAV capsid polypeptides, wherein the variant capsid polypeptides exhibit an enhanced neutralization profile, increased transduction and/or tropism in human liver tissue or hepatocyte cells (i.e., human hepatocyte cells), or both, as compared non-variant parent capsid polypeptides.
