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PROCESS FOR PREPARING A WATER-IN-OIL EMULSION COMPRISING AN IMMUNOSTIMULATORY COMPLEX
专利权人:
发明人:
SOKOLL KENNETH K
申请号:
IN3338/DELNP/2009
公开号:
IN282374B
申请日:
2009.05.22
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention provides an immunostimulatory complex specifically adapted to act as adjuvant and as a peptide immunogen stabilizer. The immunostimulatory complex comprises a CpG oligonucleotide and a biologically active peptide immunogen. The immunostimulatory complex is particulate and can efficiently present peptide immunogens to the cells of the immune system to produce an immune response. The immunostimulatory complex may be formulated as a suspension for parenteral administration. The immunostimulatory complex may also be formulated in the form of w/o-emulsions, as a suspension in combination with a mineral salt suspension or with an in-situ gelling polymer for the efficient delivery of an immunogen to the cells of the immune system of a subject following parenteral administration, to produce an immune response which may also be a protective immune response.
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中国工程科技知识中心
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