Tissue specific peptide conjugates and methods

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专利权人:

Inc.;AVI BioPharma

发明人:

Iversen, Patrick L.,Moulton, Hong M.

申请号：

AU2008271050

公开号：

AU2008271050B2

申请日:

2008.06.30

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Cell-penetrating peptides useful for targeting a therapeutic compound to aselected mammalian tissue, methods for their identification, methods of formingconjugate compounds containing such peptides, and conjugates formed therebyare disclosed. The cell-penetrating peptides are 8 to 30 amino acid residuesin length and consist of subsequences selected from the group consisting of RXR,RX, RB, and RBR； where R is arginine, B is β-alanine, and each X is independently-C(O)-(CHR

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