The present invention provides: a novel α-substituted glycineamide derivative or a pharmacologically acceptable salt thereof; a pharmaceutical composition containing the α-substituted glycineamide derivative or a pharmacologically acceptable salt thereof; and a use of the α-substituted glycineamide derivative or a pharmacologically acceptable salt thereof for medical purposes.The present invention provides a compound which has an inhibitory activity on TRPM8 and is represented by general formula (I) [wherein A