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DEVICES, METHODS, AND SYSTEMS OF FUNCTIONAL OPTICAL COHERENCE TOMOGRAPHY
专利权人:
Northwestern University
发明人:
Wenzhong Liu,Lian Duan,Hao F. Zhang,Kieren J. Patel,Hao Li,Biqin Dong,Amani A. Fawzi
申请号:
US15583615
公开号:
US20180020922A1
申请日:
2017.05.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine a flow rate of fluid in the target; angiography is also performed using one or more fast scanning methods to determine a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and be generally used for the diagnosis, monitoring and treatment of disease.
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