Charlotte Admyre,Arezou Zargari,Oliver Von Stein,Petra Von Stein
申请号:
US14359945
公开号:
US09492516B2
申请日:
2012.11.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to methods of preventing or reducing the need of colectomy. In particular, the present invention relates to an oligonucleotide, for use in the treatment of an inflammatory bowel disease, such as ulcerative colitis (UC) or Crohn's disease, in a subject that is refractory or responds insufficiently or is intolerant to anti-inflammatory therapy, wherein said oligonucleotide is repetitively administered as a single exposure.