Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
- 专利权人:
- イデラ ファーマシューティカルズ インコーポレイテッド
- 发明人:
- サドヒル・アグラワル
- 申请号:
- JP2001517689
- 公开号:
- JP5268214B2
- 申请日:
- 2000.08.14
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要:
- The invention provides methods for modulating the immune response caused by CpG-containing oligonucleotides. The methods according to the invention enable decreasing the immunostimulatory effect for antisense applications.
- 来源网站:
- 中国工程科技知识中心
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