Antibody drug conjugates (ADCs) having enzymatically cleavable groups

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专利权人:

Bayer Aktiengesellschaft;Bayer Pharma Aktiengesellschaft

发明人:

Lerchen, Hans-Georg,Rebstock, Anne-Sophie,Stelte-Ludwig, Beatrix,Kirchhoff, Dennis,Dietz, Lisa,Mahlert, Christoph,Greven, Simone,Märsch, Stephan,Berndt, Sandra,Sommer, Anette,Hammer, Stefanie

申请号：

AU2017380871

公开号：

AU2017380871A1

申请日:

2017.12.14

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The invention relates to novel antibody drug conjugates (ADCs) having improved properties, active metabolites of said ADCs and methods for the production thereof. The present invention further relates to the use of said conjugates for the treatment and/or prevention of diseases and to the use of said conjugates for the production of medicaments for the treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/