Guang Jin CHOI,Min-Jeong LEE,Nan-Hee CHUN,Keon-Hyoung SONG
申请号：
US15323063
公开号：
US20170128391A1
申请日:
2015.06.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides a preparation method for agomelatine-resorcinol and agomelatine-hydroquinone co-crystals using the solvent-antisolvent method that enables a commercial mass production. The co-crystals prepared by the preparation method of the present invention displays high dissolution rate and high stability in acidic-to-neutral media.
