MEERPOEL, LIEVEN,LINDERS, JOANNES THEODORUS MARIA,JAROSKOVA, LIBUSE,VIELLEVOYE, MARCEL,BACKX, LEO JACOBUS JOZEF,BERTHELOT, DIDIER JEAN-CLAUDE,BUSSCHER, GUUSKE FREDERIKE
申请号：
HK10100585.9
公开号：
HK1136823B
申请日:
2010.01.20
申请国别(地区):
HK
年份:
2013
代理人:
摘要：
The present invention is concerned with novel piperidine or piperazine substituted tetrahydro-naphthalene-1-carboxylic acid derivatives having apoB secretion/MTP inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of atherosclerosis, pancreatitis, obesity, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, diabetes and type II diabetes.
