The present invention relates to a system and method of giving an injection of Ringer which can grasp the living body data of the patient and the Ringer remainder data and automatically control the injection amount or the injection speed of the Ringer, or can inform this to the medical team or the protector through an external instrument and immediately change the injection condition of the Ringer according to the condition of the patient.The system and method of giving an injection of Ringer according to the present invention can comprise: a weight estimation section for measuring the weight of the Ringer bag or estimating the remainder of the Ringer a control section for receiving the data from the weight estimation section and judging and setting an injection amount or an injection speed of the Ringer and a Ringer tube opening and closing adjustment section installed at a Ringer tube connected to the Ringer bag and adjusting the injection amount or the injection speed of the Ringer by a signal received from the control section. In addition, the control section can comprise a first communication section for controlling an external instrument or an opening and closing adjustment section or for transmitting or receiving a control signal to or from the external instrument or the opening and closing adjustment section, and the opening and closing adjustment section can comprise a second communication section for transmitting or receiving the control signal to or from the external instrument or the control section.