PSMA-BINDING AGENTS AND USES THEREOF

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专利权人:

发明人:

Martin G. POMPER,Ronnie Charles MEASE,Ying CHEN

申请号：

US14987032

公开号：

US20160114060A1

申请日:

2016.01.04

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

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