THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
HARRIS, Curtis C.,HORIKAWA, Izumi,TURNQUIST, Casmir,HARRIS, Brent T.,LANE, David
申请号:
USUS2016/041631
公开号:
WO2017/008056A1
申请日:
2016.07.08
申请国别(地区):
WO
年份:
2017
代理人:
摘要:
The present invention is directed to therapies that modulate expression or activity a naturally occurring p53 isoform for the treatment of a neurodegenerative disorder in which astrocytes are dysfunctional.La présente invention concerne des thérapies qui modulent lexpression ou lactivité dun isoforme p53 existant à létat naturel pour le traitement dun trouble neurodégénératif, dans lequel les astrocytes sont dysfonctionnels.