A panning stereo endoscope which maintains an up-down orientation as the stereo endoscope pans an operative field, the panning stereo endoscope comprising:a shaft having an axis;first and second optical channels extending along the shaft, each of the first and second optical channels having an off-axis direction of view; andan actuating mechanism carried by the shaft and adapted to (i) synchronously rotate the first and second optical channels about their respective axes, and (ii) synchronously, inversely piston the first and second optical channels along their respective axes.