Condensed heteroaromatic pyrrolidinones as SYK inhibitors

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专利权人:

武田薬品工業株式会社

发明人:

有川 泰由,ジョーンズ、ベンジャミン,ラム、ベティー,ニエ、ジャ,スミス、クリストファー,高橋 昌志,ドン、キン,フェーフル、ヴィクトリア

申请号：

JP2016133849

公开号：

JP6196710B2

申请日:

2016.07.06

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L 1 , L 2 , R 1 , R 2 , R 3 , and R 4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula I, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/