The subject of the invention is laparoscopic clipping machine for application of clips on tissue structures, enclosed in a housing, comprising a pair of the movable jaws mounted on the stem, whose operational movement for clamping the clips is indirectly triggered by a movement of the handle, at least one spring, mechanism directly triggering the operational movement of the jaws comprising at least one pusher movably arranged in the axis of the stem supported in the axis of the stem on the spring characterised in that it is provided with an adjustment mechanism that adjusts the jaws output opening to at least two different positions of the jaws output opening adapted to at least two sizes of the clips, resulting in a different output angle between the jaws, wherein adjustment mechanism comprises a movable shutter element having at least two parts, the narrower part of the shutter element and the wider part of the shutter element, and the shutter element is movably guided through the through opening laterally formed in the pusher, which is larger than the wider part of the shutter element, so that the shutter element, when seated in the through opening of the pusher, partially covers the through opening light of the pusher, thus limiting the movement of the pusher when determining the output angle, in such a way, that after passing through the pusher through opening of the narrower part of the shutter element a partially limited longitudinal movement of the pusher is obtained, resulting in the first output angle, and after passing the wider part of the shutter element and its location in the pusher through opening light, a significantly limited longitudinal movement of the pusher is obtained, resulting in a second output angle.
