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isolated monoclonal antibody or antigen-binding fragment thereof, isolated nucleic acid molecule, pharmaceutical composition, and method for lowering blood glucose levels or for treating a condition or disease.
专利权人:
INC.;REGENERON PHARMACEUTICALS
发明人:
HARUKA OKAMOTO,JESPER GROMADA
申请号:
BR112017005110
公开号:
BR112017005110A2
申请日:
2015.09.15
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention provides glucagon binding antibodies and the method for their use. according to certain embodiments, the antibodies of the invention bind to high affinity human gcg. The antibodies of the invention may be completely human antibodies. The antibodies of the invention are useful for the treatment of various diseases or disorders characterized by elevated blood glucose levels as well as other gcg-related disorders.a presente invenção provê anticorpos que se ligam a glucagon e método para uso dos mesmos. de acordo com certas modalidades, os anticorpos da invenção se ligam a gcg humana com alta afinidade. os anticorpos da invenção podem ser completamente anticorpos humanos. os anticorpos da invenção são úteis para o tratamento de várias doenças ou distúrbios caracterizados por níveis elevados de glicose no sangue, assim como outros distúrbios relacionados à gcg.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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